Meprozine
Category
Meprozine Brand names, Meprozine Analogs
Meprozine Brand Names Mixture
Meprozine Chemical_Formula
C20H23NS
Meprozine RX_link
No information avaliable
Meprozine fda sheet
Meprozine msds (material safety sheet)
Meprozine Synthesis Reference
No information avaliable
Meprozine Molecular Weight
309.469 g/mol
Meprozine Melting Point
< 25 oC
Meprozine H2O Solubility
Soluble as HCl salt
Meprozine State
Liquid
Meprozine LogP
5.7
Meprozine Dosage Forms
Tablets (oral, 1 mg)
Meprozine Indication
Used for the symptomatic treatment of parkinsonism.
Meprozine Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Meprozine Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Meprozine side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Meprozine Patient Information
Meprozine Organisms Affected
Humans and other mammals
