Madiol

Madiol Brand names, Madiol Analogs

Madiol Brand Names Mixture

No information avaliable

Madiol Chemical_Formula

C₂₀H₂₃NS

Madiol RX_link

No information avaliable

Madiol fda sheet

Madiol msds (material safety sheet)

Madiol Synthesis Reference

No information avaliable

Madiol Molecular Weight

309.469 g/mol

Madiol Melting Point

< 25 ^oC

Madiol H₂O Solubility

Soluble as HCl salt

Madiol State

Liquid

Madiol LogP

5.7

Madiol Dosage Forms

Tablets (oral, 1 mg)

Madiol Indication

Used for the symptomatic treatment of parkinsonism.

Madiol Pharmacology

Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.

Madiol Absorption

Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.

Madiol side effects and Toxicity

Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Madiol Patient Information

Madiol Organisms Affected

Humans and other mammals