Categoria
Methylprednisolone
Nombres de marca,
Methylprednisolone
Analogos
Methylprednisolone
Marca los nombres de mezcla
Depo-Medrol with Lidocaine (Lidocaine Hydrochloride + Methylprednisolone Acetate) Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Sulfur) Methylprednisolone Sodium Succinate for Injection (Methylprednisolone + Water) Neo-Medrol (Methylprednisolone Acetate + Neomycin Sulfate) Neo-Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Neomycin Sulfate + Sulfur)
Methylprednisolone
Formula quimica
C22H30O5
Methylprednisolone
RX enlace
http://www.rxlist.com/cgi/generic/methprd.htm
Methylprednisolone
FDA hoja
Methylprednisolone
MSDS (hoja de seguridad de materiales)
Methylprednisolone
Sintesis de referencia
Sebek, Spero, EE.UU. Pat. 2,897,218 (1959)
Methylprednisolone
Peso molecular
374.471 g/mol
Methylprednisolone
Punto de fusion
232.5 oC
Methylprednisolone
H2O Solubilidad
120 mg / L
Methylprednisolone
Estado
Solid
Methylprednisolone
LogP
2.134
Methylprednisolone
Formas de dosificacion
Tabletas, suspensión
Methylprednisolone
Indicacion
La terapia adyuvante para administración a corto plazo en la artritis reumatoide.
Methylprednisolone
Farmacologia
Metilprednisolona y sus derivados, succinato sódico de metilprednisolona y metilprednisolona, son glucocorticoides sintéticos utilizados como agentes antiinflamatorios o inmunosupresores.
Methylprednisolone
Absorcion
La biodisponibilidad oral del 80-99%
Methylprednisolone
Toxicidad
DL50 = 2000 mg / kg (por vía oral en ratas)
Methylprednisolone
Informacion de Pacientes
Persons who are on immunosuppressant doses of corticosteroids should be warned to avoid exposure to chicken pox or
measles. Patients should also be advised that if they are exposed, medical advice should be sought without delay.
Methylprednisolone
Organismos afectados
Humanos y otros mamíferos