Warfarin
Brand names,
Warfarin
Analogs
Warfarin
Brand Names Mixture
Warfarin
Chemical_Formula
C19H16O4
Warfarin
RX_link
http://www.rxlist.com/cgi/generic/warfarin.htm
Warfarin
fda sheet
Warfarin
msds (material safety sheet)
Warfarin
Synthesis Reference
Stahmann, et al., U.S. Pat. 2,427,578 (1947)
Warfarin
Molecular Weight
308.328 g/mol
Warfarin
Melting Point
161 oC
Warfarin
H2O Solubility
17 mg/L
Warfarin
State
Solid
Warfarin
LogP
3.505
Warfarin
Dosage Forms
Powder for solution; Tablet
Warfarin
Indication
For the treatment of retinal vascular occlusion, pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, transient cerebral ischaemia, arterial embolism and thrombosis.
Warfarin
Pharmacology
Warfarin, a coumarin anticoagulant, is a racemic mixture of two active isomers. It is used in the prevention and treatment of thromboembolic disease including venous thrombosis, thromboembolism, and pulmonary embolism as well as for the prevention of ischemic stroke in patients with atrial fibrillation (AF).
Warfarin
Absorption
No information avaliable
Warfarin
side effects and Toxicity
LD50=374 (orally in mice)
Warfarin
Patient Information
No information avaliable
Warfarin
Organisms Affected
Humans and other mammals