Tintorane
Brand names,
Tintorane
Analogs
Tintorane
Brand Names Mixture
Tintorane
Chemical_Formula
C19H16O4
Tintorane
RX_link
http://www.rxlist.com/cgi/generic/warfarin.htm
Tintorane
fda sheet
Tintorane
msds (material safety sheet)
Tintorane
Synthesis Reference
Stahmann, et al., U.S. Pat. 2,427,578 (1947)
Tintorane
Molecular Weight
308.328 g/mol
Tintorane
Melting Point
161 oC
Tintorane
H2O Solubility
17 mg/L
Tintorane
State
Solid
Tintorane
LogP
3.505
Tintorane
Dosage Forms
Powder for solution; Tablet
Tintorane
Indication
For the treatment of retinal vascular occlusion, pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, transient cerebral ischaemia, arterial embolism and thrombosis.
Tintorane
Pharmacology
Warfarin, a coumarin anticoagulant, is a racemic mixture of two active isomers. It is used in the prevention and treatment of thromboembolic disease including venous thrombosis, thromboembolism, and pulmonary embolism as well as for the prevention of ischemic stroke in patients with atrial fibrillation (AF).
Tintorane
Absorption
No information avaliable
Tintorane
side effects and Toxicity
LD50=374 (orally in mice)
Tintorane
Patient Information
No information avaliable
Tintorane
Organisms Affected
Humans and other mammals