Athrombine-K
Brand names,
Athrombine-K
Analogs
Athrombine-K
Brand Names Mixture
Athrombine-K
Chemical_Formula
C19H16O4
Athrombine-K
RX_link
http://www.rxlist.com/cgi/generic/warfarin.htm
Athrombine-K
fda sheet
Athrombine-K
msds (material safety sheet)
Athrombine-K
Synthesis Reference
Stahmann, et al., U.S. Pat. 2,427,578 (1947)
Athrombine-K
Molecular Weight
308.328 g/mol
Athrombine-K
Melting Point
161 oC
Athrombine-K
H2O Solubility
17 mg/L
Athrombine-K
State
Solid
Athrombine-K
LogP
3.505
Athrombine-K
Dosage Forms
Powder for solution; Tablet
Athrombine-K
Indication
For the treatment of retinal vascular occlusion, pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, transient cerebral ischaemia, arterial embolism and thrombosis.
Athrombine-K
Pharmacology
Warfarin, a coumarin anticoagulant, is a racemic mixture of two active isomers. It is used in the prevention and treatment of thromboembolic disease including venous thrombosis, thromboembolism, and pulmonary embolism as well as for the prevention of ischemic stroke in patients with atrial fibrillation (AF).
Athrombine-K
Absorption
No information avaliable
Athrombine-K
side effects and Toxicity
LD50=374 (orally in mice)
Athrombine-K
Patient Information
No information avaliable
Athrombine-K
Organisms Affected
Humans and other mammals