Mar-Frin
Brand names,
Mar-Frin
Analogs
Mar-Frin
Brand Names Mixture
Mar-Frin
Chemical_Formula
C19H16O4
Mar-Frin
RX_link
http://www.rxlist.com/cgi/generic/warfarin.htm
Mar-Frin
fda sheet
Mar-Frin
msds (material safety sheet)
Mar-Frin
Synthesis Reference
Stahmann, et al., U.S. Pat. 2,427,578 (1947)
Mar-Frin
Molecular Weight
308.328 g/mol
Mar-Frin
Melting Point
161 oC
Mar-Frin
H2O Solubility
17 mg/L
Mar-Frin
State
Solid
Mar-Frin
LogP
3.505
Mar-Frin
Dosage Forms
Powder for solution; Tablet
Mar-Frin
Indication
For the treatment of retinal vascular occlusion, pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, transient cerebral ischaemia, arterial embolism and thrombosis.
Mar-Frin
Pharmacology
Warfarin, a coumarin anticoagulant, is a racemic mixture of two active isomers. It is used in the prevention and treatment of thromboembolic disease including venous thrombosis, thromboembolism, and pulmonary embolism as well as for the prevention of ischemic stroke in patients with atrial fibrillation (AF).
Mar-Frin
Absorption
No information avaliable
Mar-Frin
side effects and Toxicity
LD50=374 (orally in mice)
Mar-Frin
Patient Information
No information avaliable
Mar-Frin
Organisms Affected
Humans and other mammals