Warficide
Brand names,
Warficide
Analogs
Warficide
Brand Names Mixture
Warficide
Chemical_Formula
C19H16O4
Warficide
RX_link
http://www.rxlist.com/cgi/generic/warfarin.htm
Warficide
fda sheet
Warficide
msds (material safety sheet)
Warficide
Synthesis Reference
Stahmann, et al., U.S. Pat. 2,427,578 (1947)
Warficide
Molecular Weight
308.328 g/mol
Warficide
Melting Point
161 oC
Warficide
H2O Solubility
17 mg/L
Warficide
State
Solid
Warficide
LogP
3.505
Warficide
Dosage Forms
Powder for solution; Tablet
Warficide
Indication
For the treatment of retinal vascular occlusion, pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, transient cerebral ischaemia, arterial embolism and thrombosis.
Warficide
Pharmacology
Warfarin, a coumarin anticoagulant, is a racemic mixture of two active isomers. It is used in the prevention and treatment of thromboembolic disease including venous thrombosis, thromboembolism, and pulmonary embolism as well as for the prevention of ischemic stroke in patients with atrial fibrillation (AF).
Warficide
Absorption
No information avaliable
Warficide
side effects and Toxicity
LD50=374 (orally in mice)
Warficide
Patient Information
No information avaliable
Warficide
Organisms Affected
Humans and other mammals