Coumaphen
Brand names,
Coumaphen
Analogs
Coumaphen
Brand Names Mixture
Coumaphen
Chemical_Formula
C19H16O4
Coumaphen
RX_link
http://www.rxlist.com/cgi/generic/warfarin.htm
Coumaphen
fda sheet
Coumaphen
msds (material safety sheet)
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Synthesis Reference
Stahmann, et al., U.S. Pat. 2,427,578 (1947)
Coumaphen
Molecular Weight
308.328 g/mol
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Melting Point
161 oC
Coumaphen
H2O Solubility
17 mg/L
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State
Solid
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LogP
3.505
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Dosage Forms
Powder for solution; Tablet
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Indication
For the treatment of retinal vascular occlusion, pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, transient cerebral ischaemia, arterial embolism and thrombosis.
Coumaphen
Pharmacology
Warfarin, a coumarin anticoagulant, is a racemic mixture of two active isomers. It is used in the prevention and treatment of thromboembolic disease including venous thrombosis, thromboembolism, and pulmonary embolism as well as for the prevention of ischemic stroke in patients with atrial fibrillation (AF).
Coumaphen
Absorption
No information avaliable
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side effects and Toxicity
LD50=374 (orally in mice)
Coumaphen
Patient Information
No information avaliable
Coumaphen
Organisms Affected
Humans and other mammals