Athrombin
Brand names,
Athrombin
Analogs
Athrombin
Brand Names Mixture
Athrombin
Chemical_Formula
C19H16O4
Athrombin
RX_link
http://www.rxlist.com/cgi/generic/warfarin.htm
Athrombin
fda sheet
Athrombin
msds (material safety sheet)
Athrombin
Synthesis Reference
Stahmann, et al., U.S. Pat. 2,427,578 (1947)
Athrombin
Molecular Weight
308.328 g/mol
Athrombin
Melting Point
161 oC
Athrombin
H2O Solubility
17 mg/L
Athrombin
State
Solid
Athrombin
LogP
3.505
Athrombin
Dosage Forms
Powder for solution; Tablet
Athrombin
Indication
For the treatment of retinal vascular occlusion, pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, transient cerebral ischaemia, arterial embolism and thrombosis.
Athrombin
Pharmacology
Warfarin, a coumarin anticoagulant, is a racemic mixture of two active isomers. It is used in the prevention and treatment of thromboembolic disease including venous thrombosis, thromboembolism, and pulmonary embolism as well as for the prevention of ischemic stroke in patients with atrial fibrillation (AF).
Athrombin
Absorption
No information avaliable
Athrombin
side effects and Toxicity
LD50=374 (orally in mice)
Athrombin
Patient Information
No information avaliable
Athrombin
Organisms Affected
Humans and other mammals