Compound 42
Brand names,
Compound 42
Analogs
Compound 42
Brand Names Mixture
Compound 42
Chemical_Formula
C19H16O4
Compound 42
RX_link
http://www.rxlist.com/cgi/generic/warfarin.htm
Compound 42
fda sheet
Compound 42
msds (material safety sheet)
Compound 42
Synthesis Reference
Stahmann, et al., U.S. Pat. 2,427,578 (1947)
Compound 42
Molecular Weight
308.328 g/mol
Compound 42
Melting Point
161 oC
Compound 42
H2O Solubility
17 mg/L
Compound 42
State
Solid
Compound 42
LogP
3.505
Compound 42
Dosage Forms
Powder for solution; Tablet
Compound 42
Indication
For the treatment of retinal vascular occlusion, pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, transient cerebral ischaemia, arterial embolism and thrombosis.
Compound 42
Pharmacology
Warfarin, a coumarin anticoagulant, is a racemic mixture of two active isomers. It is used in the prevention and treatment of thromboembolic disease including venous thrombosis, thromboembolism, and pulmonary embolism as well as for the prevention of ischemic stroke in patients with atrial fibrillation (AF).
Compound 42
Absorption
No information avaliable
Compound 42
side effects and Toxicity
LD50=374 (orally in mice)
Compound 42
Patient Information
No information avaliable
Compound 42
Organisms Affected
Humans and other mammals