Prothromadin
Brand names,
Prothromadin
Analogs
Prothromadin
Brand Names Mixture
Prothromadin
Chemical_Formula
C19H16O4
Prothromadin
RX_link
http://www.rxlist.com/cgi/generic/warfarin.htm
Prothromadin
fda sheet
Prothromadin
msds (material safety sheet)
Prothromadin
Synthesis Reference
Stahmann, et al., U.S. Pat. 2,427,578 (1947)
Prothromadin
Molecular Weight
308.328 g/mol
Prothromadin
Melting Point
161 oC
Prothromadin
H2O Solubility
17 mg/L
Prothromadin
State
Solid
Prothromadin
LogP
3.505
Prothromadin
Dosage Forms
Powder for solution; Tablet
Prothromadin
Indication
For the treatment of retinal vascular occlusion, pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, transient cerebral ischaemia, arterial embolism and thrombosis.
Prothromadin
Pharmacology
Warfarin, a coumarin anticoagulant, is a racemic mixture of two active isomers. It is used in the prevention and treatment of thromboembolic disease including venous thrombosis, thromboembolism, and pulmonary embolism as well as for the prevention of ischemic stroke in patients with atrial fibrillation (AF).
Prothromadin
Absorption
No information avaliable
Prothromadin
side effects and Toxicity
LD50=374 (orally in mice)
Prothromadin
Patient Information
No information avaliable
Prothromadin
Organisms Affected
Humans and other mammals