Tox-Hid
Brand names,
Tox-Hid
Analogs
Tox-Hid
Brand Names Mixture
Tox-Hid
Chemical_Formula
C19H16O4
Tox-Hid
RX_link
http://www.rxlist.com/cgi/generic/warfarin.htm
Tox-Hid
fda sheet
Tox-Hid
msds (material safety sheet)
Tox-Hid
Synthesis Reference
Stahmann, et al., U.S. Pat. 2,427,578 (1947)
Tox-Hid
Molecular Weight
308.328 g/mol
Tox-Hid
Melting Point
161 oC
Tox-Hid
H2O Solubility
17 mg/L
Tox-Hid
State
Solid
Tox-Hid
LogP
3.505
Tox-Hid
Dosage Forms
Powder for solution; Tablet
Tox-Hid
Indication
For the treatment of retinal vascular occlusion, pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, transient cerebral ischaemia, arterial embolism and thrombosis.
Tox-Hid
Pharmacology
Warfarin, a coumarin anticoagulant, is a racemic mixture of two active isomers. It is used in the prevention and treatment of thromboembolic disease including venous thrombosis, thromboembolism, and pulmonary embolism as well as for the prevention of ischemic stroke in patients with atrial fibrillation (AF).
Tox-Hid
Absorption
No information avaliable
Tox-Hid
side effects and Toxicity
LD50=374 (orally in mice)
Tox-Hid
Patient Information
No information avaliable
Tox-Hid
Organisms Affected
Humans and other mammals