Warfarine
Brand names,
Warfarine
Analogs
Warfarine
Brand Names Mixture
Warfarine
Chemical_Formula
C19H16O4
Warfarine
RX_link
http://www.rxlist.com/cgi/generic/warfarin.htm
Warfarine
fda sheet
Warfarine
msds (material safety sheet)
Warfarine
Synthesis Reference
Stahmann, et al., U.S. Pat. 2,427,578 (1947)
Warfarine
Molecular Weight
308.328 g/mol
Warfarine
Melting Point
161 oC
Warfarine
H2O Solubility
17 mg/L
Warfarine
State
Solid
Warfarine
LogP
3.505
Warfarine
Dosage Forms
Powder for solution; Tablet
Warfarine
Indication
For the treatment of retinal vascular occlusion, pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, transient cerebral ischaemia, arterial embolism and thrombosis.
Warfarine
Pharmacology
Warfarin, a coumarin anticoagulant, is a racemic mixture of two active isomers. It is used in the prevention and treatment of thromboembolic disease including venous thrombosis, thromboembolism, and pulmonary embolism as well as for the prevention of ischemic stroke in patients with atrial fibrillation (AF).
Warfarine
Absorption
No information avaliable
Warfarine
side effects and Toxicity
LD50=374 (orally in mice)
Warfarine
Patient Information
No information avaliable
Warfarine
Organisms Affected
Humans and other mammals