Warfarin sodium
Brand names,
Warfarin sodium
Analogs
Warfarin sodium
Brand Names Mixture
Warfarin sodium
Chemical_Formula
C19H16O4
Warfarin sodium
RX_link
http://www.rxlist.com/cgi/generic/warfarin.htm
Warfarin sodium
fda sheet
Warfarin sodium
msds (material safety sheet)
Warfarin sodium
Synthesis Reference
Stahmann, et al., U.S. Pat. 2,427,578 (1947)
Warfarin sodium
Molecular Weight
308.328 g/mol
Warfarin sodium
Melting Point
161 oC
Warfarin sodium
H2O Solubility
17 mg/L
Warfarin sodium
State
Solid
Warfarin sodium
LogP
3.505
Warfarin sodium
Dosage Forms
Powder for solution; Tablet
Warfarin sodium
Indication
For the treatment of retinal vascular occlusion, pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, transient cerebral ischaemia, arterial embolism and thrombosis.
Warfarin sodium
Pharmacology
Warfarin, a coumarin anticoagulant, is a racemic mixture of two active isomers. It is used in the prevention and treatment of thromboembolic disease including venous thrombosis, thromboembolism, and pulmonary embolism as well as for the prevention of ischemic stroke in patients with atrial fibrillation (AF).
Warfarin sodium
Absorption
No information avaliable
Warfarin sodium
side effects and Toxicity
LD50=374 (orally in mice)
Warfarin sodium
Patient Information
No information avaliable
Warfarin sodium
Organisms Affected
Humans and other mammals