Sofarin
Brand names,
Sofarin
Analogs
Sofarin
Brand Names Mixture
Sofarin
Chemical_Formula
C19H16O4
Sofarin
RX_link
http://www.rxlist.com/cgi/generic/warfarin.htm
Sofarin
fda sheet
Sofarin
msds (material safety sheet)
Sofarin
Synthesis Reference
Stahmann, et al., U.S. Pat. 2,427,578 (1947)
Sofarin
Molecular Weight
308.328 g/mol
Sofarin
Melting Point
161 oC
Sofarin
H2O Solubility
17 mg/L
Sofarin
State
Solid
Sofarin
LogP
3.505
Sofarin
Dosage Forms
Powder for solution; Tablet
Sofarin
Indication
For the treatment of retinal vascular occlusion, pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, transient cerebral ischaemia, arterial embolism and thrombosis.
Sofarin
Pharmacology
Warfarin, a coumarin anticoagulant, is a racemic mixture of two active isomers. It is used in the prevention and treatment of thromboembolic disease including venous thrombosis, thromboembolism, and pulmonary embolism as well as for the prevention of ischemic stroke in patients with atrial fibrillation (AF).
Sofarin
Absorption
No information avaliable
Sofarin
side effects and Toxicity
LD50=374 (orally in mice)
Sofarin
Patient Information
No information avaliable
Sofarin
Organisms Affected
Humans and other mammals