Warfarat
Brand names,
Warfarat
Analogs
Warfarat
Brand Names Mixture
Warfarat
Chemical_Formula
C19H16O4
Warfarat
RX_link
http://www.rxlist.com/cgi/generic/warfarin.htm
Warfarat
fda sheet
Warfarat
msds (material safety sheet)
Warfarat
Synthesis Reference
Stahmann, et al., U.S. Pat. 2,427,578 (1947)
Warfarat
Molecular Weight
308.328 g/mol
Warfarat
Melting Point
161 oC
Warfarat
H2O Solubility
17 mg/L
Warfarat
State
Solid
Warfarat
LogP
3.505
Warfarat
Dosage Forms
Powder for solution; Tablet
Warfarat
Indication
For the treatment of retinal vascular occlusion, pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, transient cerebral ischaemia, arterial embolism and thrombosis.
Warfarat
Pharmacology
Warfarin, a coumarin anticoagulant, is a racemic mixture of two active isomers. It is used in the prevention and treatment of thromboembolic disease including venous thrombosis, thromboembolism, and pulmonary embolism as well as for the prevention of ischemic stroke in patients with atrial fibrillation (AF).
Warfarat
Absorption
No information avaliable
Warfarat
side effects and Toxicity
LD50=374 (orally in mice)
Warfarat
Patient Information
No information avaliable
Warfarat
Organisms Affected
Humans and other mammals