Eastern States Duocide
Brand names,
Eastern States Duocide
Analogs
Eastern States Duocide
Brand Names Mixture
Eastern States Duocide
Chemical_Formula
C19H16O4
Eastern States Duocide
RX_link
http://www.rxlist.com/cgi/generic/warfarin.htm
Eastern States Duocide
fda sheet
Eastern States Duocide
msds (material safety sheet)
Eastern States Duocide
Synthesis Reference
Stahmann, et al., U.S. Pat. 2,427,578 (1947)
Eastern States Duocide
Molecular Weight
308.328 g/mol
Eastern States Duocide
Melting Point
161 oC
Eastern States Duocide
H2O Solubility
17 mg/L
Eastern States Duocide
State
Solid
Eastern States Duocide
LogP
3.505
Eastern States Duocide
Dosage Forms
Powder for solution; Tablet
Eastern States Duocide
Indication
For the treatment of retinal vascular occlusion, pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, transient cerebral ischaemia, arterial embolism and thrombosis.
Eastern States Duocide
Pharmacology
Warfarin, a coumarin anticoagulant, is a racemic mixture of two active isomers. It is used in the prevention and treatment of thromboembolic disease including venous thrombosis, thromboembolism, and pulmonary embolism as well as for the prevention of ischemic stroke in patients with atrial fibrillation (AF).
Eastern States Duocide
Absorption
No information avaliable
Eastern States Duocide
side effects and Toxicity
LD50=374 (orally in mice)
Eastern States Duocide
Patient Information
No information avaliable
Eastern States Duocide
Organisms Affected
Humans and other mammals