Frass-Ratron
Brand names,
Frass-Ratron
Analogs
Frass-Ratron
Brand Names Mixture
Frass-Ratron
Chemical_Formula
C19H16O4
Frass-Ratron
RX_link
http://www.rxlist.com/cgi/generic/warfarin.htm
Frass-Ratron
fda sheet
Frass-Ratron
msds (material safety sheet)
Frass-Ratron
Synthesis Reference
Stahmann, et al., U.S. Pat. 2,427,578 (1947)
Frass-Ratron
Molecular Weight
308.328 g/mol
Frass-Ratron
Melting Point
161 oC
Frass-Ratron
H2O Solubility
17 mg/L
Frass-Ratron
State
Solid
Frass-Ratron
LogP
3.505
Frass-Ratron
Dosage Forms
Powder for solution; Tablet
Frass-Ratron
Indication
For the treatment of retinal vascular occlusion, pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, transient cerebral ischaemia, arterial embolism and thrombosis.
Frass-Ratron
Pharmacology
Warfarin, a coumarin anticoagulant, is a racemic mixture of two active isomers. It is used in the prevention and treatment of thromboembolic disease including venous thrombosis, thromboembolism, and pulmonary embolism as well as for the prevention of ischemic stroke in patients with atrial fibrillation (AF).
Frass-Ratron
Absorption
No information avaliable
Frass-Ratron
side effects and Toxicity
LD50=374 (orally in mice)
Frass-Ratron
Patient Information
No information avaliable
Frass-Ratron
Organisms Affected
Humans and other mammals