Coumafen
Brand names,
Coumafen
Analogs
Coumafen
Brand Names Mixture
Coumafen
Chemical_Formula
C19H16O4
Coumafen
RX_link
http://www.rxlist.com/cgi/generic/warfarin.htm
Coumafen
fda sheet
Coumafen
msds (material safety sheet)
Coumafen
Synthesis Reference
Stahmann, et al., U.S. Pat. 2,427,578 (1947)
Coumafen
Molecular Weight
308.328 g/mol
Coumafen
Melting Point
161 oC
Coumafen
H2O Solubility
17 mg/L
Coumafen
State
Solid
Coumafen
LogP
3.505
Coumafen
Dosage Forms
Powder for solution; Tablet
Coumafen
Indication
For the treatment of retinal vascular occlusion, pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, transient cerebral ischaemia, arterial embolism and thrombosis.
Coumafen
Pharmacology
Warfarin, a coumarin anticoagulant, is a racemic mixture of two active isomers. It is used in the prevention and treatment of thromboembolic disease including venous thrombosis, thromboembolism, and pulmonary embolism as well as for the prevention of ischemic stroke in patients with atrial fibrillation (AF).
Coumafen
Absorption
No information avaliable
Coumafen
side effects and Toxicity
LD50=374 (orally in mice)
Coumafen
Patient Information
No information avaliable
Coumafen
Organisms Affected
Humans and other mammals