200 Coumarin
Brand names,
200 Coumarin
Analogs
200 Coumarin
Brand Names Mixture
200 Coumarin
Chemical_Formula
C19H16O4
200 Coumarin
RX_link
http://www.rxlist.com/cgi/generic/warfarin.htm
200 Coumarin
fda sheet
200 Coumarin
msds (material safety sheet)
200 Coumarin
Synthesis Reference
Stahmann, et al., U.S. Pat. 2,427,578 (1947)
200 Coumarin
Molecular Weight
308.328 g/mol
200 Coumarin
Melting Point
161 oC
200 Coumarin
H2O Solubility
17 mg/L
200 Coumarin
State
Solid
200 Coumarin
LogP
3.505
200 Coumarin
Dosage Forms
Powder for solution; Tablet
200 Coumarin
Indication
For the treatment of retinal vascular occlusion, pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, transient cerebral ischaemia, arterial embolism and thrombosis.
200 Coumarin
Pharmacology
Warfarin, a coumarin anticoagulant, is a racemic mixture of two active isomers. It is used in the prevention and treatment of thromboembolic disease including venous thrombosis, thromboembolism, and pulmonary embolism as well as for the prevention of ischemic stroke in patients with atrial fibrillation (AF).
200 Coumarin
Absorption
No information avaliable
200 Coumarin
side effects and Toxicity
LD50=374 (orally in mice)
200 Coumarin
Patient Information
No information avaliable
200 Coumarin
Organisms Affected
Humans and other mammals