Brumolin
Brand names,
Brumolin
Analogs
Brumolin
Brand Names Mixture
Brumolin
Chemical_Formula
C19H16O4
Brumolin
RX_link
http://www.rxlist.com/cgi/generic/warfarin.htm
Brumolin
fda sheet
Brumolin
msds (material safety sheet)
Brumolin
Synthesis Reference
Stahmann, et al., U.S. Pat. 2,427,578 (1947)
Brumolin
Molecular Weight
308.328 g/mol
Brumolin
Melting Point
161 oC
Brumolin
H2O Solubility
17 mg/L
Brumolin
State
Solid
Brumolin
LogP
3.505
Brumolin
Dosage Forms
Powder for solution; Tablet
Brumolin
Indication
For the treatment of retinal vascular occlusion, pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, transient cerebral ischaemia, arterial embolism and thrombosis.
Brumolin
Pharmacology
Warfarin, a coumarin anticoagulant, is a racemic mixture of two active isomers. It is used in the prevention and treatment of thromboembolic disease including venous thrombosis, thromboembolism, and pulmonary embolism as well as for the prevention of ischemic stroke in patients with atrial fibrillation (AF).
Brumolin
Absorption
No information avaliable
Brumolin
side effects and Toxicity
LD50=374 (orally in mice)
Brumolin
Patient Information
No information avaliable
Brumolin
Organisms Affected
Humans and other mammals