Coumaphene
Brand names,
Coumaphene
Analogs
Coumaphene
Brand Names Mixture
Coumaphene
Chemical_Formula
C19H16O4
Coumaphene
RX_link
http://www.rxlist.com/cgi/generic/warfarin.htm
Coumaphene
fda sheet
Coumaphene
msds (material safety sheet)
Coumaphene
Synthesis Reference
Stahmann, et al., U.S. Pat. 2,427,578 (1947)
Coumaphene
Molecular Weight
308.328 g/mol
Coumaphene
Melting Point
161 oC
Coumaphene
H2O Solubility
17 mg/L
Coumaphene
State
Solid
Coumaphene
LogP
3.505
Coumaphene
Dosage Forms
Powder for solution; Tablet
Coumaphene
Indication
For the treatment of retinal vascular occlusion, pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, transient cerebral ischaemia, arterial embolism and thrombosis.
Coumaphene
Pharmacology
Warfarin, a coumarin anticoagulant, is a racemic mixture of two active isomers. It is used in the prevention and treatment of thromboembolic disease including venous thrombosis, thromboembolism, and pulmonary embolism as well as for the prevention of ischemic stroke in patients with atrial fibrillation (AF).
Coumaphene
Absorption
No information avaliable
Coumaphene
side effects and Toxicity
LD50=374 (orally in mice)
Coumaphene
Patient Information
No information avaliable
Coumaphene
Organisms Affected
Humans and other mammals