Place-Pax
Brand names,
Place-Pax
Analogs
Place-Pax
Brand Names Mixture
Place-Pax
Chemical_Formula
C19H16O4
Place-Pax
RX_link
http://www.rxlist.com/cgi/generic/warfarin.htm
Place-Pax
fda sheet
Place-Pax
msds (material safety sheet)
Place-Pax
Synthesis Reference
Stahmann, et al., U.S. Pat. 2,427,578 (1947)
Place-Pax
Molecular Weight
308.328 g/mol
Place-Pax
Melting Point
161 oC
Place-Pax
H2O Solubility
17 mg/L
Place-Pax
State
Solid
Place-Pax
LogP
3.505
Place-Pax
Dosage Forms
Powder for solution; Tablet
Place-Pax
Indication
For the treatment of retinal vascular occlusion, pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, transient cerebral ischaemia, arterial embolism and thrombosis.
Place-Pax
Pharmacology
Warfarin, a coumarin anticoagulant, is a racemic mixture of two active isomers. It is used in the prevention and treatment of thromboembolic disease including venous thrombosis, thromboembolism, and pulmonary embolism as well as for the prevention of ischemic stroke in patients with atrial fibrillation (AF).
Place-Pax
Absorption
No information avaliable
Place-Pax
side effects and Toxicity
LD50=374 (orally in mice)
Place-Pax
Patient Information
No information avaliable
Place-Pax
Organisms Affected
Humans and other mammals