Coumadin
Brand names,
Coumadin
Analogs
Coumadin
Brand Names Mixture
Coumadin
Chemical_Formula
C19H16O4
Coumadin
RX_link
http://www.rxlist.com/cgi/generic/warfarin.htm
Coumadin
fda sheet
Coumadin
msds (material safety sheet)
Coumadin
Synthesis Reference
Stahmann, et al., U.S. Pat. 2,427,578 (1947)
Coumadin
Molecular Weight
308.328 g/mol
Coumadin
Melting Point
161 oC
Coumadin
H2O Solubility
17 mg/L
Coumadin
State
Solid
Coumadin
LogP
3.505
Coumadin
Dosage Forms
Powder for solution; Tablet
Coumadin
Indication
For the treatment of retinal vascular occlusion, pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, transient cerebral ischaemia, arterial embolism and thrombosis.
Coumadin
Pharmacology
Warfarin, a coumarin anticoagulant, is a racemic mixture of two active isomers. It is used in the prevention and treatment of thromboembolic disease including venous thrombosis, thromboembolism, and pulmonary embolism as well as for the prevention of ischemic stroke in patients with atrial fibrillation (AF).
Coumadin
Absorption
No information avaliable
Coumadin
side effects and Toxicity
LD50=374 (orally in mice)
Coumadin
Patient Information
No information avaliable
Coumadin
Organisms Affected
Humans and other mammals