Kumatox
Brand names,
Kumatox
Analogs
Kumatox
Brand Names Mixture
Kumatox
Chemical_Formula
C19H16O4
Kumatox
RX_link
http://www.rxlist.com/cgi/generic/warfarin.htm
Kumatox
fda sheet
Kumatox
msds (material safety sheet)
Kumatox
Synthesis Reference
Stahmann, et al., U.S. Pat. 2,427,578 (1947)
Kumatox
Molecular Weight
308.328 g/mol
Kumatox
Melting Point
161 oC
Kumatox
H2O Solubility
17 mg/L
Kumatox
State
Solid
Kumatox
LogP
3.505
Kumatox
Dosage Forms
Powder for solution; Tablet
Kumatox
Indication
For the treatment of retinal vascular occlusion, pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, transient cerebral ischaemia, arterial embolism and thrombosis.
Kumatox
Pharmacology
Warfarin, a coumarin anticoagulant, is a racemic mixture of two active isomers. It is used in the prevention and treatment of thromboembolic disease including venous thrombosis, thromboembolism, and pulmonary embolism as well as for the prevention of ischemic stroke in patients with atrial fibrillation (AF).
Kumatox
Absorption
No information avaliable
Kumatox
side effects and Toxicity
LD50=374 (orally in mice)
Kumatox
Patient Information
No information avaliable
Kumatox
Organisms Affected
Humans and other mammals