Solfa
Brand names,
Solfa
Analogs
Solfa
Brand Names Mixture
Solfa
Chemical_Formula
C19H16O4
Solfa
RX_link
http://www.rxlist.com/cgi/generic/warfarin.htm
Solfa
fda sheet
Solfa
msds (material safety sheet)
Solfa
Synthesis Reference
Stahmann, et al., U.S. Pat. 2,427,578 (1947)
Solfa
Molecular Weight
308.328 g/mol
Solfa
Melting Point
161 oC
Solfa
H2O Solubility
17 mg/L
Solfa
State
Solid
Solfa
LogP
3.505
Solfa
Dosage Forms
Powder for solution; Tablet
Solfa
Indication
For the treatment of retinal vascular occlusion, pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, transient cerebral ischaemia, arterial embolism and thrombosis.
Solfa
Pharmacology
Warfarin, a coumarin anticoagulant, is a racemic mixture of two active isomers. It is used in the prevention and treatment of thromboembolic disease including venous thrombosis, thromboembolism, and pulmonary embolism as well as for the prevention of ischemic stroke in patients with atrial fibrillation (AF).
Solfa
Absorption
No information avaliable
Solfa
side effects and Toxicity
LD50=374 (orally in mice)
Solfa
Patient Information
No information avaliable
Solfa
Organisms Affected
Humans and other mammals