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Proma Brand names, Proma Analogs

Proma Brand Names Mixture

  • Depo-Medrol with Lidocaine (Lidocaine Hydrochloride + Methylprednisolone Acetate)
  • Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Sulfur)
  • Methylprednisolone Sodium Succinate for Injection (Methylprednisolone + Water)
  • Neo-Medrol (Methylprednisolone Acetate + Neomycin Sulfate)
  • Neo-Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Neomycin Sulfate + Sulfur)

Proma Chemical_Formula

C22H30O5

Proma RX_link

http://www.rxlist.com/cgi/generic/methprd.htm

Proma fda sheet

Proma FDA

Proma msds (material safety sheet)

Proma MSDS

Proma Synthesis Reference

Sebek, Spero, U.S. Pat. 2,897,218 (1959)

Proma Molecular Weight

374.471 g/mol

Proma Melting Point

232.5 oC

Proma H2O Solubility

120 mg/L

Proma State

Solid

Proma LogP

2.134

Proma Dosage Forms

Tablets; Suspension

Proma Indication

Adjunctive therapy for short-term administration in rheumatoid arthritis.

Proma Pharmacology

Methylprednisolone and its derivatives, methylprednisolone sodium succinate and methylprednisolone acetate, are synthetic glucocorticoids used as antiinflammatory or immunosuppressive agents.

Proma Absorption

Oral bioavailability 80-99%

Proma side effects and Toxicity

LD50=2000 mg/kg (orally in rat)

Proma Patient Information

Persons who are on immunosuppressant doses of corticosteroids should be warned to avoid exposure to chicken pox or measles. Patients should also be advised that if they are exposed, medical advice should be sought without delay.

 

Proma Organisms Affected

Humans and other mammals