pms-Pyrazinamide
Brand names,
pms-Pyrazinamide
Analogs
pms-Pyrazinamide
Brand Names Mixture
pms-Pyrazinamide
Chemical_Formula
C43H51N3O11
pms-Pyrazinamide
RX_link
http://www.rxlist.com/cgi/generic/xifaxan.htm
pms-Pyrazinamide
fda sheet
pms-Pyrazinamide
msds (material safety sheet)
pms-Pyrazinamide
Synthesis Reference
No information avaliable
pms-Pyrazinamide
Molecular Weight
785.879 g/mol
pms-Pyrazinamide
Melting Point
No information avaliable
pms-Pyrazinamide
H2O Solubility
No information avaliable
pms-Pyrazinamide
State
No information avaliable
pms-Pyrazinamide
LogP
4.161
pms-Pyrazinamide
Dosage Forms
No information avaliable
pms-Pyrazinamide
Indication
For the treatment of patients (>=12 years of age) with travelers' diarrhea caused by noninvasive strains of Escherichia coli.
pms-Pyrazinamide
Pharmacology
Rifaximin is a structural analog of rifampin and non-systemic, gastrointestinal site-specific antibiotic. Rifaximin acts by inhibiting bacterial ribonucleic acid (RNA) synthesis. While an increase in pulmonary hydrogen excretion is evident in diverticular disease, the therapeutic effect of rifaximin does not appear to be due to a persistent correction of this alteration and the drug appears to cause no significant imbalance in the intestinal ecosystem.
pms-Pyrazinamide
Absorption
Low absorption in both the fasting state and when administered within 30 minutes of a high-fat breakfast.
pms-Pyrazinamide
side effects and Toxicity
LD50 > 2 g/kg (orally, in rats)
pms-Pyrazinamide
Patient Information
No information avaliable
pms-Pyrazinamide
Organisms Affected
Enteric bacteria and eubacteria