Pyrazide
Brand names,
Pyrazide
Analogs
Pyrazide
Brand Names Mixture
Pyrazide
Chemical_Formula
C43H51N3O11
Pyrazide
RX_link
http://www.rxlist.com/cgi/generic/xifaxan.htm
Pyrazide
fda sheet
Pyrazide
msds (material safety sheet)
Pyrazide
Synthesis Reference
No information avaliable
Pyrazide
Molecular Weight
785.879 g/mol
Pyrazide
Melting Point
No information avaliable
Pyrazide
H2O Solubility
No information avaliable
Pyrazide
State
No information avaliable
Pyrazide
LogP
4.161
Pyrazide
Dosage Forms
No information avaliable
Pyrazide
Indication
For the treatment of patients (>=12 years of age) with travelers' diarrhea caused by noninvasive strains of Escherichia coli.
Pyrazide
Pharmacology
Rifaximin is a structural analog of rifampin and non-systemic, gastrointestinal site-specific antibiotic. Rifaximin acts by inhibiting bacterial ribonucleic acid (RNA) synthesis. While an increase in pulmonary hydrogen excretion is evident in diverticular disease, the therapeutic effect of rifaximin does not appear to be due to a persistent correction of this alteration and the drug appears to cause no significant imbalance in the intestinal ecosystem.
Pyrazide
Absorption
Low absorption in both the fasting state and when administered within 30 minutes of a high-fat breakfast.
Pyrazide
side effects and Toxicity
LD50 > 2 g/kg (orally, in rats)
Pyrazide
Patient Information
No information avaliable
Pyrazide
Organisms Affected
Enteric bacteria and eubacteria