Lynamide
Brand names,
Lynamide
Analogs
Lynamide
Brand Names Mixture
Lynamide
Chemical_Formula
C43H51N3O11
Lynamide
RX_link
http://www.rxlist.com/cgi/generic/xifaxan.htm
Lynamide
fda sheet
Lynamide
msds (material safety sheet)
Lynamide
Synthesis Reference
No information avaliable
Lynamide
Molecular Weight
785.879 g/mol
Lynamide
Melting Point
No information avaliable
Lynamide
H2O Solubility
No information avaliable
Lynamide
State
No information avaliable
Lynamide
LogP
4.161
Lynamide
Dosage Forms
No information avaliable
Lynamide
Indication
For the treatment of patients (>=12 years of age) with travelers' diarrhea caused by noninvasive strains of Escherichia coli.
Lynamide
Pharmacology
Rifaximin is a structural analog of rifampin and non-systemic, gastrointestinal site-specific antibiotic. Rifaximin acts by inhibiting bacterial ribonucleic acid (RNA) synthesis. While an increase in pulmonary hydrogen excretion is evident in diverticular disease, the therapeutic effect of rifaximin does not appear to be due to a persistent correction of this alteration and the drug appears to cause no significant imbalance in the intestinal ecosystem.
Lynamide
Absorption
Low absorption in both the fasting state and when administered within 30 minutes of a high-fat breakfast.
Lynamide
side effects and Toxicity
LD50 > 2 g/kg (orally, in rats)
Lynamide
Patient Information
No information avaliable
Lynamide
Organisms Affected
Enteric bacteria and eubacteria