Novamid
Brand names,
Novamid
Analogs
Novamid
Brand Names Mixture
Novamid
Chemical_Formula
C43H51N3O11
Novamid
RX_link
http://www.rxlist.com/cgi/generic/xifaxan.htm
Novamid
fda sheet
Novamid
msds (material safety sheet)
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Synthesis Reference
No information avaliable
Novamid
Molecular Weight
785.879 g/mol
Novamid
Melting Point
No information avaliable
Novamid
H2O Solubility
No information avaliable
Novamid
State
No information avaliable
Novamid
LogP
4.161
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Dosage Forms
No information avaliable
Novamid
Indication
For the treatment of patients (>=12 years of age) with travelers' diarrhea caused by noninvasive strains of Escherichia coli.
Novamid
Pharmacology
Rifaximin is a structural analog of rifampin and non-systemic, gastrointestinal site-specific antibiotic. Rifaximin acts by inhibiting bacterial ribonucleic acid (RNA) synthesis. While an increase in pulmonary hydrogen excretion is evident in diverticular disease, the therapeutic effect of rifaximin does not appear to be due to a persistent correction of this alteration and the drug appears to cause no significant imbalance in the intestinal ecosystem.
Novamid
Absorption
Low absorption in both the fasting state and when administered within 30 minutes of a high-fat breakfast.
Novamid
side effects and Toxicity
LD50 > 2 g/kg (orally, in rats)
Novamid
Patient Information
No information avaliable
Novamid
Organisms Affected
Enteric bacteria and eubacteria