Aldinamid
Brand names,
Aldinamid
Analogs
Aldinamid
Brand Names Mixture
Aldinamid
Chemical_Formula
C43H51N3O11
Aldinamid
RX_link
http://www.rxlist.com/cgi/generic/xifaxan.htm
Aldinamid
fda sheet
Aldinamid
msds (material safety sheet)
Aldinamid
Synthesis Reference
No information avaliable
Aldinamid
Molecular Weight
785.879 g/mol
Aldinamid
Melting Point
No information avaliable
Aldinamid
H2O Solubility
No information avaliable
Aldinamid
State
No information avaliable
Aldinamid
LogP
4.161
Aldinamid
Dosage Forms
No information avaliable
Aldinamid
Indication
For the treatment of patients (>=12 years of age) with travelers' diarrhea caused by noninvasive strains of Escherichia coli.
Aldinamid
Pharmacology
Rifaximin is a structural analog of rifampin and non-systemic, gastrointestinal site-specific antibiotic. Rifaximin acts by inhibiting bacterial ribonucleic acid (RNA) synthesis. While an increase in pulmonary hydrogen excretion is evident in diverticular disease, the therapeutic effect of rifaximin does not appear to be due to a persistent correction of this alteration and the drug appears to cause no significant imbalance in the intestinal ecosystem.
Aldinamid
Absorption
Low absorption in both the fasting state and when administered within 30 minutes of a high-fat breakfast.
Aldinamid
side effects and Toxicity
LD50 > 2 g/kg (orally, in rats)
Aldinamid
Patient Information
No information avaliable
Aldinamid
Organisms Affected
Enteric bacteria and eubacteria