Aldinamide
Brand names,
Aldinamide
Analogs
Aldinamide
Brand Names Mixture
Aldinamide
Chemical_Formula
C43H51N3O11
Aldinamide
RX_link
http://www.rxlist.com/cgi/generic/xifaxan.htm
Aldinamide
fda sheet
Aldinamide
msds (material safety sheet)
Aldinamide
Synthesis Reference
No information avaliable
Aldinamide
Molecular Weight
785.879 g/mol
Aldinamide
Melting Point
No information avaliable
Aldinamide
H2O Solubility
No information avaliable
Aldinamide
State
No information avaliable
Aldinamide
LogP
4.161
Aldinamide
Dosage Forms
No information avaliable
Aldinamide
Indication
For the treatment of patients (>=12 years of age) with travelers' diarrhea caused by noninvasive strains of Escherichia coli.
Aldinamide
Pharmacology
Rifaximin is a structural analog of rifampin and non-systemic, gastrointestinal site-specific antibiotic. Rifaximin acts by inhibiting bacterial ribonucleic acid (RNA) synthesis. While an increase in pulmonary hydrogen excretion is evident in diverticular disease, the therapeutic effect of rifaximin does not appear to be due to a persistent correction of this alteration and the drug appears to cause no significant imbalance in the intestinal ecosystem.
Aldinamide
Absorption
Low absorption in both the fasting state and when administered within 30 minutes of a high-fat breakfast.
Aldinamide
side effects and Toxicity
LD50 > 2 g/kg (orally, in rats)
Aldinamide
Patient Information
No information avaliable
Aldinamide
Organisms Affected
Enteric bacteria and eubacteria