Pirazinamid
Brand names,
Pirazinamid
Analogs
Pirazinamid
Brand Names Mixture
Pirazinamid
Chemical_Formula
C43H51N3O11
Pirazinamid
RX_link
http://www.rxlist.com/cgi/generic/xifaxan.htm
Pirazinamid
fda sheet
Pirazinamid
msds (material safety sheet)
Pirazinamid
Synthesis Reference
No information avaliable
Pirazinamid
Molecular Weight
785.879 g/mol
Pirazinamid
Melting Point
No information avaliable
Pirazinamid
H2O Solubility
No information avaliable
Pirazinamid
State
No information avaliable
Pirazinamid
LogP
4.161
Pirazinamid
Dosage Forms
No information avaliable
Pirazinamid
Indication
For the treatment of patients (>=12 years of age) with travelers' diarrhea caused by noninvasive strains of Escherichia coli.
Pirazinamid
Pharmacology
Rifaximin is a structural analog of rifampin and non-systemic, gastrointestinal site-specific antibiotic. Rifaximin acts by inhibiting bacterial ribonucleic acid (RNA) synthesis. While an increase in pulmonary hydrogen excretion is evident in diverticular disease, the therapeutic effect of rifaximin does not appear to be due to a persistent correction of this alteration and the drug appears to cause no significant imbalance in the intestinal ecosystem.
Pirazinamid
Absorption
Low absorption in both the fasting state and when administered within 30 minutes of a high-fat breakfast.
Pirazinamid
side effects and Toxicity
LD50 > 2 g/kg (orally, in rats)
Pirazinamid
Patient Information
No information avaliable
Pirazinamid
Organisms Affected
Enteric bacteria and eubacteria