Unipyranamide
Brand names,
Unipyranamide
Analogs
Unipyranamide
Brand Names Mixture
Unipyranamide
Chemical_Formula
C43H51N3O11
Unipyranamide
RX_link
http://www.rxlist.com/cgi/generic/xifaxan.htm
Unipyranamide
fda sheet
Unipyranamide
msds (material safety sheet)
Unipyranamide
Synthesis Reference
No information avaliable
Unipyranamide
Molecular Weight
785.879 g/mol
Unipyranamide
Melting Point
No information avaliable
Unipyranamide
H2O Solubility
No information avaliable
Unipyranamide
State
No information avaliable
Unipyranamide
LogP
4.161
Unipyranamide
Dosage Forms
No information avaliable
Unipyranamide
Indication
For the treatment of patients (>=12 years of age) with travelers' diarrhea caused by noninvasive strains of Escherichia coli.
Unipyranamide
Pharmacology
Rifaximin is a structural analog of rifampin and non-systemic, gastrointestinal site-specific antibiotic. Rifaximin acts by inhibiting bacterial ribonucleic acid (RNA) synthesis. While an increase in pulmonary hydrogen excretion is evident in diverticular disease, the therapeutic effect of rifaximin does not appear to be due to a persistent correction of this alteration and the drug appears to cause no significant imbalance in the intestinal ecosystem.
Unipyranamide
Absorption
Low absorption in both the fasting state and when administered within 30 minutes of a high-fat breakfast.
Unipyranamide
side effects and Toxicity
LD50 > 2 g/kg (orally, in rats)
Unipyranamide
Patient Information
No information avaliable
Unipyranamide
Organisms Affected
Enteric bacteria and eubacteria