Pirazimida
Brand names,
Pirazimida
Analogs
Pirazimida
Brand Names Mixture
Pirazimida
Chemical_Formula
C43H51N3O11
Pirazimida
RX_link
http://www.rxlist.com/cgi/generic/xifaxan.htm
Pirazimida
fda sheet
Pirazimida
msds (material safety sheet)
Pirazimida
Synthesis Reference
No information avaliable
Pirazimida
Molecular Weight
785.879 g/mol
Pirazimida
Melting Point
No information avaliable
Pirazimida
H2O Solubility
No information avaliable
Pirazimida
State
No information avaliable
Pirazimida
LogP
4.161
Pirazimida
Dosage Forms
No information avaliable
Pirazimida
Indication
For the treatment of patients (>=12 years of age) with travelers' diarrhea caused by noninvasive strains of Escherichia coli.
Pirazimida
Pharmacology
Rifaximin is a structural analog of rifampin and non-systemic, gastrointestinal site-specific antibiotic. Rifaximin acts by inhibiting bacterial ribonucleic acid (RNA) synthesis. While an increase in pulmonary hydrogen excretion is evident in diverticular disease, the therapeutic effect of rifaximin does not appear to be due to a persistent correction of this alteration and the drug appears to cause no significant imbalance in the intestinal ecosystem.
Pirazimida
Absorption
Low absorption in both the fasting state and when administered within 30 minutes of a high-fat breakfast.
Pirazimida
side effects and Toxicity
LD50 > 2 g/kg (orally, in rats)
Pirazimida
Patient Information
No information avaliable
Pirazimida
Organisms Affected
Enteric bacteria and eubacteria