Pirilene
Brand names,
Pirilene
Analogs
Pirilene
Brand Names Mixture
Pirilene
Chemical_Formula
C43H51N3O11
Pirilene
RX_link
http://www.rxlist.com/cgi/generic/xifaxan.htm
Pirilene
fda sheet
Pirilene
msds (material safety sheet)
Pirilene
Synthesis Reference
No information avaliable
Pirilene
Molecular Weight
785.879 g/mol
Pirilene
Melting Point
No information avaliable
Pirilene
H2O Solubility
No information avaliable
Pirilene
State
No information avaliable
Pirilene
LogP
4.161
Pirilene
Dosage Forms
No information avaliable
Pirilene
Indication
For the treatment of patients (>=12 years of age) with travelers' diarrhea caused by noninvasive strains of Escherichia coli.
Pirilene
Pharmacology
Rifaximin is a structural analog of rifampin and non-systemic, gastrointestinal site-specific antibiotic. Rifaximin acts by inhibiting bacterial ribonucleic acid (RNA) synthesis. While an increase in pulmonary hydrogen excretion is evident in diverticular disease, the therapeutic effect of rifaximin does not appear to be due to a persistent correction of this alteration and the drug appears to cause no significant imbalance in the intestinal ecosystem.
Pirilene
Absorption
Low absorption in both the fasting state and when administered within 30 minutes of a high-fat breakfast.
Pirilene
side effects and Toxicity
LD50 > 2 g/kg (orally, in rats)
Pirilene
Patient Information
No information avaliable
Pirilene
Organisms Affected
Enteric bacteria and eubacteria