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Pyrazineamide Brand names, Pyrazineamide Analogs

Pyrazineamide Brand Names Mixture

  • No information avaliable

Pyrazineamide Chemical_Formula

C43H51N3O11

Pyrazineamide RX_link

http://www.rxlist.com/cgi/generic/xifaxan.htm

Pyrazineamide fda sheet

Pyrazineamide FDA

Pyrazineamide msds (material safety sheet)

Pyrazineamide MSDS

Pyrazineamide Synthesis Reference

No information avaliable

Pyrazineamide Molecular Weight

785.879 g/mol

Pyrazineamide Melting Point

No information avaliable

Pyrazineamide H2O Solubility

No information avaliable

Pyrazineamide State

No information avaliable

Pyrazineamide LogP

4.161

Pyrazineamide Dosage Forms

No information avaliable

Pyrazineamide Indication

For the treatment of patients (>=12 years of age) with travelers' diarrhea caused by noninvasive strains of Escherichia coli.

Pyrazineamide Pharmacology

Rifaximin is a structural analog of rifampin and non-systemic, gastrointestinal site-specific antibiotic. Rifaximin acts by inhibiting bacterial ribonucleic acid (RNA) synthesis. While an increase in pulmonary hydrogen excretion is evident in diverticular disease, the therapeutic effect of rifaximin does not appear to be due to a persistent correction of this alteration and the drug appears to cause no significant imbalance in the intestinal ecosystem.

Pyrazineamide Absorption

Low absorption in both the fasting state and when administered within 30 minutes of a high-fat breakfast.

Pyrazineamide side effects and Toxicity

LD50 > 2 g/kg (orally, in rats)

Pyrazineamide Patient Information

No information avaliable

Pyrazineamide Organisms Affected

Enteric bacteria and eubacteria