Braccopiral
Brand names,
Braccopiral
Analogs
Braccopiral
Brand Names Mixture
Braccopiral
Chemical_Formula
C43H51N3O11
Braccopiral
RX_link
http://www.rxlist.com/cgi/generic/xifaxan.htm
Braccopiral
fda sheet
Braccopiral
msds (material safety sheet)
Braccopiral
Synthesis Reference
No information avaliable
Braccopiral
Molecular Weight
785.879 g/mol
Braccopiral
Melting Point
No information avaliable
Braccopiral
H2O Solubility
No information avaliable
Braccopiral
State
No information avaliable
Braccopiral
LogP
4.161
Braccopiral
Dosage Forms
No information avaliable
Braccopiral
Indication
For the treatment of patients (>=12 years of age) with travelers' diarrhea caused by noninvasive strains of Escherichia coli.
Braccopiral
Pharmacology
Rifaximin is a structural analog of rifampin and non-systemic, gastrointestinal site-specific antibiotic. Rifaximin acts by inhibiting bacterial ribonucleic acid (RNA) synthesis. While an increase in pulmonary hydrogen excretion is evident in diverticular disease, the therapeutic effect of rifaximin does not appear to be due to a persistent correction of this alteration and the drug appears to cause no significant imbalance in the intestinal ecosystem.
Braccopiral
Absorption
Low absorption in both the fasting state and when administered within 30 minutes of a high-fat breakfast.
Braccopiral
side effects and Toxicity
LD50 > 2 g/kg (orally, in rats)
Braccopiral
Patient Information
No information avaliable
Braccopiral
Organisms Affected
Enteric bacteria and eubacteria