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PZA Brand names, PZA Analogs

PZA Brand Names Mixture

  • No information avaliable

PZA Chemical_Formula

C43H51N3O11

PZA RX_link

http://www.rxlist.com/cgi/generic/xifaxan.htm

PZA fda sheet

PZA FDA

PZA msds (material safety sheet)

PZA MSDS

PZA Synthesis Reference

No information avaliable

PZA Molecular Weight

785.879 g/mol

PZA Melting Point

No information avaliable

PZA H2O Solubility

No information avaliable

PZA State

No information avaliable

PZA LogP

4.161

PZA Dosage Forms

No information avaliable

PZA Indication

For the treatment of patients (>=12 years of age) with travelers' diarrhea caused by noninvasive strains of Escherichia coli.

PZA Pharmacology

Rifaximin is a structural analog of rifampin and non-systemic, gastrointestinal site-specific antibiotic. Rifaximin acts by inhibiting bacterial ribonucleic acid (RNA) synthesis. While an increase in pulmonary hydrogen excretion is evident in diverticular disease, the therapeutic effect of rifaximin does not appear to be due to a persistent correction of this alteration and the drug appears to cause no significant imbalance in the intestinal ecosystem.

PZA Absorption

Low absorption in both the fasting state and when administered within 30 minutes of a high-fat breakfast.

PZA side effects and Toxicity

LD50 > 2 g/kg (orally, in rats)

PZA Patient Information

No information avaliable

PZA Organisms Affected

Enteric bacteria and eubacteria