Rozide
Brand names,
Rozide
Analogs
Rozide
Brand Names Mixture
Rozide
Chemical_Formula
C43H51N3O11
Rozide
RX_link
http://www.rxlist.com/cgi/generic/xifaxan.htm
Rozide
fda sheet
Rozide
msds (material safety sheet)
Rozide
Synthesis Reference
No information avaliable
Rozide
Molecular Weight
785.879 g/mol
Rozide
Melting Point
No information avaliable
Rozide
H2O Solubility
No information avaliable
Rozide
State
No information avaliable
Rozide
LogP
4.161
Rozide
Dosage Forms
No information avaliable
Rozide
Indication
For the treatment of patients (>=12 years of age) with travelers' diarrhea caused by noninvasive strains of Escherichia coli.
Rozide
Pharmacology
Rifaximin is a structural analog of rifampin and non-systemic, gastrointestinal site-specific antibiotic. Rifaximin acts by inhibiting bacterial ribonucleic acid (RNA) synthesis. While an increase in pulmonary hydrogen excretion is evident in diverticular disease, the therapeutic effect of rifaximin does not appear to be due to a persistent correction of this alteration and the drug appears to cause no significant imbalance in the intestinal ecosystem.
Rozide
Absorption
Low absorption in both the fasting state and when administered within 30 minutes of a high-fat breakfast.
Rozide
side effects and Toxicity
LD50 > 2 g/kg (orally, in rats)
Rozide
Patient Information
No information avaliable
Rozide
Organisms Affected
Enteric bacteria and eubacteria