Pyramide
Brand names,
Pyramide
Analogs
Pyramide
Brand Names Mixture
Pyramide
Chemical_Formula
C43H51N3O11
Pyramide
RX_link
http://www.rxlist.com/cgi/generic/xifaxan.htm
Pyramide
fda sheet
Pyramide
msds (material safety sheet)
Pyramide
Synthesis Reference
No information avaliable
Pyramide
Molecular Weight
785.879 g/mol
Pyramide
Melting Point
No information avaliable
Pyramide
H2O Solubility
No information avaliable
Pyramide
State
No information avaliable
Pyramide
LogP
4.161
Pyramide
Dosage Forms
No information avaliable
Pyramide
Indication
For the treatment of patients (>=12 years of age) with travelers' diarrhea caused by noninvasive strains of Escherichia coli.
Pyramide
Pharmacology
Rifaximin is a structural analog of rifampin and non-systemic, gastrointestinal site-specific antibiotic. Rifaximin acts by inhibiting bacterial ribonucleic acid (RNA) synthesis. While an increase in pulmonary hydrogen excretion is evident in diverticular disease, the therapeutic effect of rifaximin does not appear to be due to a persistent correction of this alteration and the drug appears to cause no significant imbalance in the intestinal ecosystem.
Pyramide
Absorption
Low absorption in both the fasting state and when administered within 30 minutes of a high-fat breakfast.
Pyramide
side effects and Toxicity
LD50 > 2 g/kg (orally, in rats)
Pyramide
Patient Information
No information avaliable
Pyramide
Organisms Affected
Enteric bacteria and eubacteria