Piraldina
Brand names,
Piraldina
Analogs
Piraldina
Brand Names Mixture
Piraldina
Chemical_Formula
C43H51N3O11
Piraldina
RX_link
http://www.rxlist.com/cgi/generic/xifaxan.htm
Piraldina
fda sheet
Piraldina
msds (material safety sheet)
Piraldina
Synthesis Reference
No information avaliable
Piraldina
Molecular Weight
785.879 g/mol
Piraldina
Melting Point
No information avaliable
Piraldina
H2O Solubility
No information avaliable
Piraldina
State
No information avaliable
Piraldina
LogP
4.161
Piraldina
Dosage Forms
No information avaliable
Piraldina
Indication
For the treatment of patients (>=12 years of age) with travelers' diarrhea caused by noninvasive strains of Escherichia coli.
Piraldina
Pharmacology
Rifaximin is a structural analog of rifampin and non-systemic, gastrointestinal site-specific antibiotic. Rifaximin acts by inhibiting bacterial ribonucleic acid (RNA) synthesis. While an increase in pulmonary hydrogen excretion is evident in diverticular disease, the therapeutic effect of rifaximin does not appear to be due to a persistent correction of this alteration and the drug appears to cause no significant imbalance in the intestinal ecosystem.
Piraldina
Absorption
Low absorption in both the fasting state and when administered within 30 minutes of a high-fat breakfast.
Piraldina
side effects and Toxicity
LD50 > 2 g/kg (orally, in rats)
Piraldina
Patient Information
No information avaliable
Piraldina
Organisms Affected
Enteric bacteria and eubacteria