Eprazin
Brand names,
Eprazin
Analogs
Eprazin
Brand Names Mixture
Eprazin
Chemical_Formula
C43H51N3O11
Eprazin
RX_link
http://www.rxlist.com/cgi/generic/xifaxan.htm
Eprazin
fda sheet
Eprazin
msds (material safety sheet)
Eprazin
Synthesis Reference
No information avaliable
Eprazin
Molecular Weight
785.879 g/mol
Eprazin
Melting Point
No information avaliable
Eprazin
H2O Solubility
No information avaliable
Eprazin
State
No information avaliable
Eprazin
LogP
4.161
Eprazin
Dosage Forms
No information avaliable
Eprazin
Indication
For the treatment of patients (>=12 years of age) with travelers' diarrhea caused by noninvasive strains of Escherichia coli.
Eprazin
Pharmacology
Rifaximin is a structural analog of rifampin and non-systemic, gastrointestinal site-specific antibiotic. Rifaximin acts by inhibiting bacterial ribonucleic acid (RNA) synthesis. While an increase in pulmonary hydrogen excretion is evident in diverticular disease, the therapeutic effect of rifaximin does not appear to be due to a persistent correction of this alteration and the drug appears to cause no significant imbalance in the intestinal ecosystem.
Eprazin
Absorption
Low absorption in both the fasting state and when administered within 30 minutes of a high-fat breakfast.
Eprazin
side effects and Toxicity
LD50 > 2 g/kg (orally, in rats)
Eprazin
Patient Information
No information avaliable
Eprazin
Organisms Affected
Enteric bacteria and eubacteria