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Respramin Brand names, Respramin Analogs

Respramin Brand Names Mixture

  • No information avaliable

Respramin Chemical_Formula


Respramin RX_link

Respramin fda sheet

Respramin FDA

Respramin msds (material safety sheet)

Respramin MSDS

Respramin Synthesis Reference

No information avaliable

Respramin Molecular Weight

131.173 g/mol

Respramin Melting Point

205 oC

Respramin H2O Solubility

5.05E+005 mg/L

Respramin State


Respramin LogP


Respramin Dosage Forms

Solution for injection (containing 250 mg/mL of aminocaproic acid) and tablets (500, 1000mg)

Respramin Indication

For use in the treatment of excessive postoperative bleeding.

Respramin Pharmacology

Aminocaproic acid works as an antifibrinolytic. It is a derivative of the amino acid lysine. The fibrinolysis-inhibitory effects of aminocaproic acid appear to be exerted principally via inhibition of plasminogen activators and to a lesser degree through antiplasmin activity.

Respramin Absorption

Absorbed rapidly following oral administration. In adults, oral absorption appears to be a zero-order process with an absorption rate of 5.2 g/hr. The mean lag time in absorption is 10 minutes. After a single oral dose of 5 g, absorption was complete (F=1).

Respramin side effects and Toxicity

A few cases of acute overdosage with intravenous administration have been reported. The effects have ranged from no reaction to transient hypotension to severe acute renal failure leading to death. The intravenous and oral LD50 were 3.0 and 12.0 g/kg respectively in the mouse and 3.2 and 16.4 g/kg respectively in the rat. An intravenous infusion dose of 2.3 g/kg was lethal in the dog.

Respramin Patient Information

Respramin Organisms Affected

Humans and other mammals