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Acepramin Brand names, Acepramin Analogs

Acepramin Brand Names Mixture

  • No information avaliable

Acepramin Chemical_Formula


Acepramin RX_link

Acepramin fda sheet

Acepramin FDA

Acepramin msds (material safety sheet)

Acepramin MSDS

Acepramin Synthesis Reference

No information avaliable

Acepramin Molecular Weight

131.173 g/mol

Acepramin Melting Point

205 oC

Acepramin H2O Solubility

5.05E+005 mg/L

Acepramin State


Acepramin LogP


Acepramin Dosage Forms

Solution for injection (containing 250 mg/mL of aminocaproic acid) and tablets (500, 1000mg)

Acepramin Indication

For use in the treatment of excessive postoperative bleeding.

Acepramin Pharmacology

Aminocaproic acid works as an antifibrinolytic. It is a derivative of the amino acid lysine. The fibrinolysis-inhibitory effects of aminocaproic acid appear to be exerted principally via inhibition of plasminogen activators and to a lesser degree through antiplasmin activity.

Acepramin Absorption

Absorbed rapidly following oral administration. In adults, oral absorption appears to be a zero-order process with an absorption rate of 5.2 g/hr. The mean lag time in absorption is 10 minutes. After a single oral dose of 5 g, absorption was complete (F=1).

Acepramin side effects and Toxicity

A few cases of acute overdosage with intravenous administration have been reported. The effects have ranged from no reaction to transient hypotension to severe acute renal failure leading to death. The intravenous and oral LD50 were 3.0 and 12.0 g/kg respectively in the mouse and 3.2 and 16.4 g/kg respectively in the rat. An intravenous infusion dose of 2.3 g/kg was lethal in the dog.

Acepramin Patient Information

Acepramin Organisms Affected

Humans and other mammals