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Atsemin Brand names, Atsemin Analogs

Atsemin Brand Names Mixture

  • No information avaliable

Atsemin Chemical_Formula


Atsemin RX_link

Atsemin fda sheet

Atsemin FDA

Atsemin msds (material safety sheet)

Atsemin MSDS

Atsemin Synthesis Reference

No information avaliable

Atsemin Molecular Weight

131.173 g/mol

Atsemin Melting Point

205 oC

Atsemin H2O Solubility

5.05E+005 mg/L

Atsemin State


Atsemin LogP


Atsemin Dosage Forms

Solution for injection (containing 250 mg/mL of aminocaproic acid) and tablets (500, 1000mg)

Atsemin Indication

For use in the treatment of excessive postoperative bleeding.

Atsemin Pharmacology

Aminocaproic acid works as an antifibrinolytic. It is a derivative of the amino acid lysine. The fibrinolysis-inhibitory effects of aminocaproic acid appear to be exerted principally via inhibition of plasminogen activators and to a lesser degree through antiplasmin activity.

Atsemin Absorption

Absorbed rapidly following oral administration. In adults, oral absorption appears to be a zero-order process with an absorption rate of 5.2 g/hr. The mean lag time in absorption is 10 minutes. After a single oral dose of 5 g, absorption was complete (F=1).

Atsemin side effects and Toxicity

A few cases of acute overdosage with intravenous administration have been reported. The effects have ranged from no reaction to transient hypotension to severe acute renal failure leading to death. The intravenous and oral LD50 were 3.0 and 12.0 g/kg respectively in the mouse and 3.2 and 16.4 g/kg respectively in the rat. An intravenous infusion dose of 2.3 g/kg was lethal in the dog.

Atsemin Patient Information

Atsemin Organisms Affected

Humans and other mammals