Capranol en es it fr

Capranol Brand names, Capranol Analogs

Capranol Brand Names Mixture

  • No information avaliable

Capranol Chemical_Formula


Capranol RX_link

Capranol fda sheet

Capranol FDA

Capranol msds (material safety sheet)

Capranol MSDS

Capranol Synthesis Reference

No information avaliable

Capranol Molecular Weight

131.173 g/mol

Capranol Melting Point

205 oC

Capranol H2O Solubility

5.05E+005 mg/L

Capranol State


Capranol LogP


Capranol Dosage Forms

Solution for injection (containing 250 mg/mL of aminocaproic acid) and tablets (500, 1000mg)

Capranol Indication

For use in the treatment of excessive postoperative bleeding.

Capranol Pharmacology

Aminocaproic acid works as an antifibrinolytic. It is a derivative of the amino acid lysine. The fibrinolysis-inhibitory effects of aminocaproic acid appear to be exerted principally via inhibition of plasminogen activators and to a lesser degree through antiplasmin activity.

Capranol Absorption

Absorbed rapidly following oral administration. In adults, oral absorption appears to be a zero-order process with an absorption rate of 5.2 g/hr. The mean lag time in absorption is 10 minutes. After a single oral dose of 5 g, absorption was complete (F=1).

Capranol side effects and Toxicity

A few cases of acute overdosage with intravenous administration have been reported. The effects have ranged from no reaction to transient hypotension to severe acute renal failure leading to death. The intravenous and oral LD50 were 3.0 and 12.0 g/kg respectively in the mouse and 3.2 and 16.4 g/kg respectively in the rat. An intravenous infusion dose of 2.3 g/kg was lethal in the dog.

Capranol Patient Information

Capranol Organisms Affected

Humans and other mammals