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Amicar Brand names, Amicar Analogs

Amicar Brand Names Mixture

  • No information avaliable

Amicar Chemical_Formula


Amicar RX_link

Amicar fda sheet

Amicar FDA

Amicar msds (material safety sheet)

Amicar MSDS

Amicar Synthesis Reference

No information avaliable

Amicar Molecular Weight

131.173 g/mol

Amicar Melting Point

205 oC

Amicar H2O Solubility

5.05E+005 mg/L

Amicar State


Amicar LogP


Amicar Dosage Forms

Solution for injection (containing 250 mg/mL of aminocaproic acid) and tablets (500, 1000mg)

Amicar Indication

For use in the treatment of excessive postoperative bleeding.

Amicar Pharmacology

Aminocaproic acid works as an antifibrinolytic. It is a derivative of the amino acid lysine. The fibrinolysis-inhibitory effects of aminocaproic acid appear to be exerted principally via inhibition of plasminogen activators and to a lesser degree through antiplasmin activity.

Amicar Absorption

Absorbed rapidly following oral administration. In adults, oral absorption appears to be a zero-order process with an absorption rate of 5.2 g/hr. The mean lag time in absorption is 10 minutes. After a single oral dose of 5 g, absorption was complete (F=1).

Amicar side effects and Toxicity

A few cases of acute overdosage with intravenous administration have been reported. The effects have ranged from no reaction to transient hypotension to severe acute renal failure leading to death. The intravenous and oral LD50 were 3.0 and 12.0 g/kg respectively in the mouse and 3.2 and 16.4 g/kg respectively in the rat. An intravenous infusion dose of 2.3 g/kg was lethal in the dog.

Amicar Patient Information

Amicar Organisms Affected

Humans and other mammals